22 May 2024 --- Shiseido says it discovered for “the first time in the world” that odorant binding protein (OBP) 2A protects the skin from odor molecules. The skin care giant asserts that the protein aids in creating homeostasis in the epidermis and plays a part in the epidermal barrier. OBP2A, found inside the human nose, is known to filter out stress molecules that damage cells. When the skin was immunostained (a process identifying a specific protein), Shiseido found OBP2A was also present in the epidermis.